1. You are here:
  2. Research
  3. Research Articles
  4. 2015 Articles

2015 Articles

A novel HPLC-MS/MS method for the simultaneous determination of astemizole and its major metabolite in dog or monkey plasma and application to pharmacokinetics.
Back HM, Lee JH, Chae JW, Song B, Seo JW, Yun HY, Kwon KI.
J. Pharm. Biomed. Anal., 2015, 114, 121–126.
Abstract

Pharmacokinetic modeling and Monte Carlo simulation of ondansetron following oral administration in dogs.
Baek LH, Lee BY, Kang J, Kwon KI.
J. Vet. Pharmacol. Ther., 2015, 38, 199–202.
Abstract

Confirmation and quantification of clenbuterol in horse urine using liquid chromatography tandem mass spectrometry triple quadrupole.
Bishop J, Heffron B, Taddei L, Benoit M, Hurt L, Costello S, Gross M, Negrusz A.
J. Anal. Toxicol., 2015, 39, 130–132.
Abstract

Pharmacokinetic evaluation of immediate- and extended-release formulations of levetiracetam in dogs.
Boozer LB, Platt SR, Haley AC, Linville AV, Kent M, Barron LE, Nie B, Arnold RD.
Am. J. Vet. Res., 2015, 76, 719–23.
Abstract

Determination of influence of food intake after a single oral dose of mosapride in beagle dogs using nonlinear mixed effect modeling.
Chae JW, Hwang JA, Baek IH, Pradhan S, Song B, Back HM, Yun M, Pai C, Bang JS, Yun HY, Kang W, Kwon KI.
J. Vet. Pharmacol. Ther., 2015, 38, 590–595.
Abstract

Effects of food intake on pharmacokinetics of mosapride in beagle dogs.
Chae JW, Song BJ, Baek IH, Yun HY, Ma JY, Kwon KI.
J. Vet. Pharmacol. Ther., 2015, 38, 497–499.
Abstract

Pharmacokinetics and pharmacodynamics comparison between subcutaneous and intravenous butorphanol administration in horses.
Chiavaccini L, Claude AK, Lee JH, Ross MK, Meyer RE, Langston VC.
J. Vet. Pharmacol. Ther., 2015, 38, 365–374.
Abstract

A validated UHPLC-MS/MS method to quantify low levels of anabolic-androgenic steroids naturally present in urine of untreated horses.
Decloedt A, Bailly-Chouriberry L, Vanden Bussche J, Garcia P, Popot MA, Bonnaire Y, Vanhaecke L.
Anal. Bioanal. Chem., 2015, 407, 4385–4396.
Abstract

In vitro simulation of the equine hindgut as a tool to study the influence of phytosterol consumption on the excretion of anabolic-androgenic steroids in horses.
Decloedt AI, Bailly-Chouriberry L, Vanden Bussche J, Garcia P, Popot MA, Bonnaire Y, Vanhaecke L.
J. Steroid Biochem. Mol. Biol., 2015, 152, 180–192.
Abstract

Intra-articular administration of lidocaine in anaesthetized dogs: pharmacokinetic profile and safety on cardiovascular and nervous systems.
Di Salvo A, Bufalari A, De Monte V, Cagnardi P, Marenzoni ML, Catanzaro A, Vigorito V, della Rocca G.
J. Vet. Pharmacol. Ther., 2015, 38, 350–356.
Abstract

Plasma concentration-dependent suppression of endogenous hydrocortisone in the horse after intramuscular administration of dexamethasone-21-isonicotinate.
Ekstrand C, Bondesson U, Gabrielsson J, Hedeland M, Kallings P, Olsén L, Ingvast-Larsson C.
J. Vet. Pharmacol. Ther., 2015, 38, 235–242.
Abstract

UPLC-MS/MS for the determination of azilsartan in beagle dog plasma and its application in a pharmacokinetics study.
Gong C, Wang J, Sun Y, Ding D, Zhong L, Zhu M, Sun J, Zhang X.
Asian J. Pharm. Sci., 2015, 10, 247–253.
Abstract

Pharmacokinetic and pharmacodynamic analysis comparing diverse effects of detomidine, medetomidine, and dexmedetomidine in the horse: a population analysis.
Grimsrud KN, Ait-Oudhia S, Durbin-Johnson BP, Rocke DM, Mama KR, Rezende ML, Stanley SD, Jusko WJ.
J. Vet. Pharmacol. Ther., 2015, 38, 24–34.
Abstract

Characterization of equine urinary metabolites of selective androgen receptor modulators (SARMs) S1, S4 and S22 for doping control purposes.
Hansson A, Knych H, Stanley S, Thevis M, Bondesson U, Hedeland M.
Drug Test. Anal., 2015, 7, 673–683.
Abstract

Equine total carbon dioxide testing in Illinois in 2012.
Heffron B, Benoit M, Bishop J, Costello S, Hurt L, Simpson L, Taddei L, Kline K, Negrusz A.
J. Anal. Toxicol., 2015, 38, 536–540.
Abstract

Controlling the misuse of cobalt in horses.
Ho EN, Chan GH, Wan TS, Curl P, Riggs CM, Hurley MJ, Sykes D.
Drug Test. Anal., 2015, 7, 21–30.
Abstract

Control of the misuse of testosterone in castrated horses based on an international threshold in plasma.
Ho ENM, Kwok WH, Leung DKK, Riggs CM, Sidlow G, Stewart BD, Wong ASY, Wan TSM.
Drug Test Anal., 2015, 7, 414–419.
Abstract

Pharmacokinetics and pharmacodynamics of three formulations of firocoxib in healthy horses.
Holland B, Fogle C, Blikslager AT, Curling A, Barlow BM, Schirmer J, Davis JL.
J. Vet. Pharmacol. Ther., 2015, 38, 249–256.
Abstract

Analysis of metronidazole in equine plasma using liquid chromatography/tandem mass spectrometry and high-resolution accurate mass spectrometry.
Ilomuanya M, Uboh C, Ciallella J, Li X, Liu Y, Ifudu N, Azubuike C, Igwilo C.
Rapid Commun. Mass Spectrom., 2015, 29, 753–763.
Abstract

Plasma concentrations of lidocaine in dogs following lidocaine patch application over an incision compared to intact skin.
Joudrey SD, Robinson DA, Kearney MT, Papich MG, da Cunha AF.
J. Vet. Pharmacol. Ther., 2015, 38, 575–580.
Abstract

Pharmacokinetics and effects on thromboxane B2 production following intravenous administration of flunixin meglumine to exercised thoroughbred horses.
Knych HK, Arthur RM, McKemie DS, Chapman N.
J. Vet. Pharmacol. Ther., 2015, 38, 313–320.
Abstract

Pharmacokinetics and selected pharmacodynamics of cobalt following a single intravenous administration to horses.
Knych HK, Arthur RM, Mitchell MM, Holser I, Poppenga R, Smith LL, Helm MN, Sams RA, Gaskill CL.
Drug Test. Anal., 2015, 7, 619–625.
Abstract

Disposition and metabolic profile of the weak androgen dehydroepiandrosterone (DHEA) following administration as part of a nutritional supplement to exercised horses.
Knych HK, Arthur RM, Stanley SD, McKemie DS.
Drug Test. Anal., 2015, 7, 39–47.
Abstract

Effects of age on the pharmacokinetics and selected pharmacodynamics of intravenously administered fentanyl in foals.
Knych HK, Steffey EP, Mitchell MM, Casbeer HC.
Equine Vet. J., 2015, 47, 72–77.
Abstract

Endogenous concentrations, pharmacokinetics, and selected pharmacodynamic effects of a single dose of exogenous GABA in horses.
Knych HK, Steinmetz SJ, McKemie DS.
J. Vet. Pharmacol. Ther., 2015, 38, 113–122.
Abstract

Absorption, elimination and cerebrospinal fluid concentrations of nimodipine in healthy beagle dogs receiving human intravenous and oral formulation.
Koskimäki J, Tarkia M, Ahtola-Sätilä T, Saloranta L, Laakso A, Frantzén J.
Eur. J. Drug Metab. Pharmacokinet.
Abstract

In vitro metabolism studies of desoxy-methyltestosterone (DMT) and its five analogues, and in vivo metabolism of desoxy-vinyltestosterone (DVT) in horses.
Kwok WH, Kwok KY, Leung DKK, Leung GNW, Wong CHF, Wong JKY, Wan TSM.
J. Mass Spectrom., 2015, 50, 994–1005.
Abstract

Metabolic study of androsta-1,4,6-triene-3,17-dione in horses using liquid chromatography/high resolution mass spectrometry.
Kwok WH, Leung GN, Wan TS, Curl P, Schiff PJ.
J. Steroid Biochem. Mol. Biol., 2015, 152, 142–154.
Abstract

Chloramphenicol significantly affects the pharmacokinetics of oral methadone in greyhound dogs.
KuKanich B, KuKanich K.
Vet. Anaesth. Analg., 2015, 42, 597–607.
Abstract

Pharmacokinetics, pharmacodynamics, toxicology and therapeutics of mavacoxib in the dog: a review.
Lees P, Pelligand L, Elliott J, Toutain PL, Michels G, Stegemann M.
J. Vet. Pharmacol. Ther., 2015, 38, 1–14.
Abstract

Simultaneous determination of triamcinolone acetonide palmitate and triamcinolone acetonide in beagle dog plasma by UPLC-MS/MS and its application to a long-term pharmacokinetic study of triamcinolone acetonide palmitate lipid emulsion injection.
Liu H, Yang M, Wu P, Guan J, Men L, Lin H, Tang X, Zhao Y.
J. Pharm. Biomed. Anal., 2015, 104, 105–111.
Abstract

Pharmacokinetic-pharmacodynamic modelling of intravenous buprenorphine in conscious horses.
Love EJ, Pelligand L, Taylor PM, Murrell JC, Sear JW.
Vet. Anaesth. Analg., 2015, 42, 17–29.
Abstract

Effects of a GnRH administration on testosterone profile, libido and semen parameters of dromedary camel bulls.
Monaco D, Fatnassi M, Padalino B, Aubé L, Khorchani T, Hammadi M, Lacalandra GM.
Res. Vet. Sci., 2015, 102, 212–216.
Abstract

Evaluation of the pharmacokinetics of oral amitriptyline and its active metabolite nortriptyline in fed and fasted Greyhound dogs.
Norkus C, Rankin D, KuKanich B.
J. Vet. Pharmacol. Ther., 2015, 38, 619–622.
Abstract

Pharmacokinetics of intravenous and oral amitriptyline and its active metabolite nortriptyline in greyhound dogs.
Norkus C, Rankin D, KuKanich B.
Vet. Anaesth. Analg, 2015, 42, 580–589.
Abstract

Pharmacokinetics of oral amantadine in greyhound dogs.
Norkus C, Rankin D, Warner M, KuKanich B.
J. Vet. Pharmacol. Ther., 2015, 38, 305–308.
Abstract

Pharmacokinetics of propafenone hydrochloride sustained-release capsules in male beagle dogs.
Pan L, Qian Y, Cheng M, Gu P, He Y, Xu X, Ding L.
Acta Pharm. Sin. B, 2015, 5, 74–78.
Abstract

Development and validation of an LC-MS/MS method for the determination of mesalazine in beagle dog plasma and its application to a pharmacokinetic study.
Qin J, Di X, Wang X, Liu Y.
Biomed. Chromatogr., 2014, 29, 261–267.
Abstract

The pharmacokinetics of dexmedetomidine administered as a constant rate infusion in horses.
Ranheim B, Risberg AI, Spadavecchia C, Landsem R, Haga HA.
J. Vet. Pharmacol. Ther., 2015, 38, 93–96.
Abstract

Pharmacokinetics of pergolide after intravenous administration to horses.
Rendle DI, Hughes KJ, Doran GS, Edwards SH.
Am. J. Vet. Res., 2015, 76, 155–160.
Abstract

Pharmacokinetics and pharmacodynamics of intravenous dexmedetomidine in the horse.
Rezende ML, Grimsrud KN, Stanley SD, Steffey EP, Mama KR.
J. Vet. Pharmacol. Ther., 2015, 38, 15–23.
Abstract

Pharmacokinetics and pharmacodynamics of dermorphin in the horse.
Robinson MA, Guan F, McDonnell S, Uboh CE, Soma LR.
J. Vet. Pharmacol. Ther., 2015, 38, 321–329.
Abstract

Pharmacokinetics of metronidazole in foals: influence of age within the neonatal period.
Swain EA, Magdesian KG, Kass PH, Edman JE, Knych HK.
J. Vet. Pharmacol. Ther., 2015, 38, 227–234.
Abstract

Pharmacokinetics of intravenous, plain oral and enteric-coated oral omeprazole in the horse.
Sykes BW, Underwood C, McGowan CM, Mills PC.
J. Vet. Pharmacol. Ther., 2015, 38, 130–136.
Abstract

Simultaneous determination of telmisartan and amlodipine in dog plasma by LC-MS-MS.
Wang B, Sheng L, Li Y.
J. Chromatogr. Sci., 2015, 53, 1708–1713.
Abstract

Determination of lansoprazole enantiomers in dog plasma by column-switching liquid chromatography with tandem mass spectrometry and its application to a preclinical pharmacokinetic study.
Wang H, Sun Y, Meng X, Yang B, Wang J, Yang Y, Gu J.
J. Sep. Sci., 2015, 38, 2960–2967.
Abstract

Plasma ibuprofen enantiomers and their pharmacokinetics in Beagle dogs determined by HPLC.
Wang HY, Kong AY, Yang B, Yan LP, Di X.
Yao Xue Xue Bao., 2015, 50, 1607–1612.
Abstract

Detection and pharmacokinetics of salbutamol in thoroughbred racehorses following inhaled administration.
Wieder ME, Paine SW, Hincks PR, Pearce CM, Scarth J, Hillyer L.
J. Vet. Pharmacol. Ther., 2015, 38, 41–47.
Abstract

Metabolic studies of oxyguno in horses.
Wong AS, Ho EN, Wan TS, Lam KK, Stewart BD.
Anal. Chim. Acta, 2015, 891, 190–202.
Abstract

Liquid chromatography-mass spectrometry analysis of five bisphosphonates in equine urine and plasma.
Wong AS, Ho EN, Wan TS, Lam KK, Stewart BD.
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2015, 998–999, 1–7.
Abstract

Pharmacokinetics and physiologic effects of alprazolam after a single oral dose in healthy mares.
Wong DM, Davis JL, Alcott CJ, Hepworth-Warren KL, Galow-Kersh NL, Rice S, Coetzee JF.
J. Vet. Pharmacol. Ther., 2015, 38, 301–304.
Abstract