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2018 Articles

Pharmacokinetic and pharmacodynamic properties of orally administered torsemide in healthy horses.
Agne GF, Jung SW, Wooldridge AA, Duran SH, Ravis W, Toribio R.
J. Vet. Intern. Med., DOI 10.1111/jvim.15213.

The pharmacokinetics of cytarabine administered subcutaneously, combined with prednisone, in dogs with meningoencephalomyelitis of unknown etiology.
Pastina B, Early PJ, Bergman RL, Nettifee J, Maller A, Bray KY, Waldron RJ, Castel AM, Munana KR, Papich MG, Messenger KM.
Pharmacokinet. Report, DOI 10.1111/jvp.12667.

Quantification of doping compounds in faecal samples from racing pigeons, by liquid chromatography-tandem mass spectrometry.
Moreira FX, Silva R, André MB, de Pinho PG, Bastos ML, Ruivo J, Ruivo P, Carmo H.
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., DOI 10.1016/j.jchromb.2018.05.004.

Determination of d-amphetamine and diphenhydramine in beagle dog plasma by a 96-well formatted liquid-liquid extraction and capillary zone electrophoresis with field-amplified sample stacking.
Li J, Zhang L, Cheng X, Zhang L, Shen B, Qing C, Fan G.
J. Pharm. Biomed. Anal., DOI 10.1016/j.jpba.2018.04.040.

Application of a sensitive and specific LC-ESI-MS/MS method for the simultaneous quantification of twelve bioactive components in dog plasma for an intravenous pharmacokinetic study of Yiqifumai Injection in Beagle dogs.
Zhang F, Qiao X, Lu H, Zhang S, Du W, Xiao X.
Biomed. Chromatogr., DOI 10.1002/bmc.4256.

Gut microbiota-regulated pharmacokinetics of berberine and active metabolites in Beagle dogs after oral administration.
Feng R, Zhao ZX, Ma SR, Guo F, Wang Y, Jiang JD.
Front. Pharmacol., DOI 10.3389/fphar.2018.00214.

Detection and pharmacokinetics of grapiprant following oral administration to exercised Thoroughbred horses.
Knych HK, Seminoff K, McKemie DS.
Drug Test. Anal., DOI 10.1002/dta.2378.

Metabolic study of methylstenbolone in horses using liquid chromatography-high resolution mass spectrometry and gas chromatography-mass spectrometry.
Choi TLS, Wong JKY, Kwok WH, Curl P, Mechie S, Wan TSM.
J. Chromatogr. A, DOI 10.1016/j.chroma.2018.02.041.

Analysis of loxoprofen in tablets, patches and equine urine as tert-butyldimethylsilyl derivative by gas chromatography-mass spectrometry.
Kim Y, Seo C, Oh S, Kwak J, Jung S, Sin E, Kim H, Ji M, Lee HS, Park HJ, Lee G, Yu J, Kim M, Lee W, Paik MJ.
Arch. Pharm. Res., DOI 10.1007/s12272-018-1023-5.

Quantitative determination of meloxicam in dog plasma by high performance liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study.
Tian Y, Wu X, Zhang M, Zhao L, Xiong Z, Qin F.
Biomed. Chromatogr., DOI 10.1002/bmc.4228.

The pharmacokinetics study of ginkgolide A, B and the effect of food on bioavailability after oral administration of ginkgolide extracts in beagle dogs.
Aa L, Fei F, Tan Z, Aa J, Wang G, Liu C.
Biomed. Chromatogr., DOI 10.1002/bmc.4212.

The pharmacokinetics and analgesic effects of extended-release buprenorphine administered subcutaneously in healthy dogs.
Barletta M, Ostenkamp SM, Taylor AC, Quandt J, Lascelles BDX, Messenger KM.
J. Vet. Pharmacol. Ther., DOI 10.1111/jvp.12497.

Prediction of human pharmacokinetics of ulixertinib, a novel ERK1/2 inhibitor from mice, rats, and dogs pharmacokinetics.
Suresh PS, Jairam RK, Chandrasekhar DV, Vinod AB, Hiremath RA, Raj A, Zainuddin M, Bhamidipati RK, Mullangi R.
Eur. J. Drug Metab. Pharmacokinet., DOI 10.1007/s13318-018-0465-y.

Pharmacokinetics, pharmacodynamics, and metabolism of acepromazine following intravenous, oral, and sublingual administration to exercised Thoroughbred horses.
Knych HK, Seminoff K, McKemie DS, Kass PH.
J. Vet. Pharmacol. Ther., DOI 10.1111/jvp.12494.

Detection of prohibited substances in equine hair by ultra-high performance liquid chromatography-triple quadrupole mass spectrometry – application to doping control samples.
Gray B, Viljanto M, Menzies E, Vanhaecke L.
Drug Test. Anal., DOI 10.1002/dta.2367.

Determination of human insulin in dog plasma by a selective liquid chromatography-tandem mass spectrometry method: Application to a pharmacokinetic study.
Dong S, Zeng Y, Wei G, Si D, Liu C.
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., DOI 10.1016/j.jchromb.2017.12.029.

Accurate determination of a novel vasodilatory β-blocker TJ0711 using LC-MS/MS: resolution of an isobaric metabolite interference in dog plasma.
Hu Y, Zhu W, Guan Y, Wu S, Zhang X, Li G, Si L, Huang J.
Biomed. Chromatogr., DOI 10.1002/bmc.4196.

A validated LC-MS/MS method for the determination of senkyunolide I in dog plasma and its application to a pharmacokinetic and bioavailability studies.
Li JQ, Wang JF, Li J, Zhang SH, He D, Tong RS, She SY.
Biomed. Chromatogr., DOI 10.1002/bmc.4182.

Pharmacokinetics of single-dose sildenafil administered orally in clinically healthy dogs: effect of feeding and dose proportionality.
Akabane R, Sato T, Sakatani A, Miyagawa Y, Tazaki H, Takemura N.
J. Vet Pharmacol. Ther., 2018, 41, 457‐462.

Pharmacokinetic evaluation of novel midazolam gel formulations following buccal administration to healthy dogs.
Aldawsari MF, Lau VW, Babu RJ, Arnold RD, Platt SR.
Am. J. Vet. Res., 2018, 79, 73–82.

In vitro anti-LPS dose determination of ketorolac tromethamine and in vivo safety of repeated dosing in healthy horses.
Bianco AW, Moore GE, Cooper BR, Taylor SD.
J. Vet. Pharmacol. Ther., 2018, 41, 98–104.

Disposition of levetiracetam in healthy adult horses.
Cesar FB, Stewart AJ, Boothe DM, Ravis WR, Duran SH, Wooldridge AA.
Vet. Pharmacol. Ther., 2018, 41, 92–97.

LC-ESI-MS/MS determination of 4-methylpyrazole in dog plasma and its application to a pharmacokinetic study in dogs.
Chandrasekhar DV, S SP, Dittakavi S, Hiremath RA, Bhamidipati RK, Richter W, Srinivas NR, Mullangi R.
Biomed. Chromatogr., 2018, 32, e4065.

Pharmacokinetics, pharmacodynamics and clinical use of trazodone and its active metabolite m-chlorophenylpiperazine in the horse.
Davis JL, Schirmer J, Medlin E.
J. Vet Pharmacol. Ther., 2018, 41, 393–401.

Determination of testosterone esters in the hair of male greyhound dogs using liquid chromatography high resolution mass spectrometry.
Devi JL, Zahra P, Vine JH, Whittem T.
Drug Test. Anal., 2018, 10, 460–473.

Postoperative pharmacokinetics of meloxicam in horses after surgery for colic syndrome.
Di Salvo A, Giorgo M, Nannarone S, Lee HK, Corsalini J, della Rocca G.
J. Vet. Pharmacol. Ther., 2018, 41, 369–373.

Pharmacokinetic profiles of the active metamizole metabolites after four different routes of administration in healthy dogs.
Giorgi M, Łebkowska-Wieruszewska B, Lisowski A, Owen H, Poapolathep A, Kim TW, De Vito V.
J. Vet Pharmacol. Ther., 2018, 41, 428–436.

Detection and confirmation of α-cobratoxin in equine plasma by solid-phase extraction and liquid chromatography coupled to mass spectrometry.
Guan F, You Y, Li X, Robinson MA.
J. Chromatogr. A, 2018, 1533, 38–48.

Bioavailability and tolerability of nebulised dexamethasone sodium phosphate in adult horses.
Haspel AD, Giguère S, Hart KA, Berghaus LJ, Davis JL.
Equine Vet. J., 2018, 50, 85–90.

Pharmacokinetics and safety of oral glyburide in dogs with acute spinal cord injury.
Jeffery N, Boudreau CE, Konarik M, Mays T, Fajt V.
PeerJ, 2018, 6, e4387.

Pharmacokinetics of furosemide administered 4 and 24 hours prior to high-speed exercise in horses.
Knych HK, Vale A, Wilson WD, Kass PH, Arthur RM, Jones JH.
J. Vet. Pharmacol. Ther., 2018, 41, 224–229.

Pharmacogenetics of opioid analgesics in dogs.
Kongara K.
J. Vet. Pharmacol. Ther., 2018, 41, 195–204.

Metoclopramide nasal spray in vitro evaluation and in vivo pharmacokinetic studies in dogs.
Li Y, Fan X, Li W, Yang P, Zhang H, Tang D, Yin X, Sun J, Zheng A.
Pharm. Dev. Technol., 2018, 23, 275–281.

A novel and innovative hair test to determine glucocorticoid levels in racing camels for use in assessment of doping, health and disease.
Shah I, Haddow JD, Ibrahim HA, Sheikh MVA, Alhemeiri FSA.
Drug Test. Anal., 2018, 10, 742–749.

Pharmacokinetics, disposition, and plasma concentrations of dimethyl sulfoxide (DMSO) in the horse following topical, oral, and intravenous administration.
Soma LR, Robinson MA, You Y, Boston RC, Rudy J.
J. Vet Pharmacol. Ther., 2018, 41, 384–392.

Re-evaluation of the regulation of omeprazole in racehorses: An evidence-based approach.
Viljanto M, Hillyer L, Hincks P, Pearce C, Paine SW.
J. Vet. Pharmacol. Ther., 2018, 41, 469‐475.