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2017 Articles

Pharmacokinetics and electrophysiological effects of sotalol hydrochloride in horses.
Broux B, De Clercq D, Decloedt A, Vera L, Devreese M, Gehring R, Croubels S, van Loon G.
Equine Vet. J., DOI 10.1111/evj.12765.
Abstract

A novel and innovative hair test to determine glucocorticoid levels in racing camels for use in assessment of doping, health and disease.
Shah I, Haddow JD, Ibrahim HA, Sheikh MVA, Alhemeiri FSA.
Drug Test. Anal., DOI 10.1002/dta.2311.
Abstract

A validated UPLC-MS/MS method coupled with protein precipitation and ion exchange solid phase extraction for the quantitation of porcine relaxin B29 in dog plasma and its application to a pharmacokinetic study.
Su C, Sun H, Yang H, Yin L, Zhang J, Fawcett JP, Gu J.
Anal. Bioanal. Chem., DOI 10.1007/s00216-017-0604-3.
Abstract

Pharmacogenetics of opioid analgesics in dogs.
Kongara K.
J. Vet. Pharmacol. Ther., DOI 10.1111/jvp.12452.
Abstract

LC-ESI-MS/MS determination of 4-methylpyrazole in dog plasma and its application to a pharmacokinetic study in dogs.
Chandrasekhar DV, S SP, Dittakavi S, Hiremath RA, Bhamidipati RK, Richter W, Srinivas NR, Mullangi R.
Biomed. Chromatogr., DOI 10.1002/bmc.4065.
Abstract

Pharmacokinetic profile of intra-articular fluticasone propionate microparticles in beagle dog knees.
Getgood A, Dhollander A,2, Malone A, Price J, Helliwell J.
Cartilage, DOI 10.1177/1947603517723687.
Abstract

Pharmacokinetics and dynamics of mycophenolate mofetil after single-dose oral administration in juvenile dachshunds.
Grobman M, Boothe DM, Rindt H, Williamson BG, Katz ML, Coates JR, Reinero CR.
J. Vet. Pharmacol. Ther., DOI 10.1111/jvp.12420.
Abstract

A physiologically based model for tramadol pharmacokinetics in horses.
Abbiati RA, Cagnardi P, Ravasio G, Villa R, Manca D.
J. Theor. Biol., DOI 10.1016/j.jtbi.2017.06.028.
Abstract

Online turbulent flow extraction coupled with liquid chromatography-tandem mass spectrometry for high throughput screening of anabolic steroids in horse urine.
Shin HD, Suh JH, Kim J, Cho HD, Lee SD, Han KS, Wang Y, Han SB.
J. Pharm. Biomed. Anal., DOI 10.1016/j.jpba.2017.06.036.
Abstract

Determination of testosterone esters in the hair of male greyhound dogs using liquid chromatography high resolution mass spectrometry.
Devi JL, Zahra P, Vine JH, Whittem T.
Drug Test. Anal., DOI 10.1002/dta.2236.
Abstract

Bioavailability and tolerability of nebulised dexamethasone sodium phosphate in adult horses.
Haspel AD, Giguère S, Hart KA, Berghaus LJ, Davis JL.
Equine Vet. J., DOI 10.1111/evj.12724.
Abstract

The effects of ketoconazole and cimetidine on the pharmacokinetics of oral tramadol in greyhound dogs.
KuKanich B, KuKanich K, Black J.
J. Vet. Pharmacol. Ther., DOI 10.1111/jvp.12424.
Abstract

In vitro anti-LPS dose determination of ketorolac tromethamine and in vivo safety of repeated dosing in healthy horses.
Bianco AW, Moore GE, Cooper BR, Taylor SD.
J. Vet. Pharmacol. Ther., DFOI 10.1111/jvp.12425.
Abstract

Plasma concentration and cardiovascular effects of intramuscular medetomidine combined with three doses of the peripheral alpha2-antagonist MK-467 in dogs.
Restitutti F, Kaartinen MJ, Raekallio MR, Wejberg O, Mikkola E, Del Castillo JRE, Scheinin M, Vainio OM.
Vet. Anaesth. Analg., DOI 10.1016/j.vaa.2016.04.006.
Abstract

Sensitive LC-MS/MS method for the simultaneous determination of bendamustine and its active metabolite, γ-hydroxybendamustine in small volume mice and dog plasma and its application to a pharmacokinetic study in mice and dogs.
Chandrashekar DV, Suresh PS, Kumar R, Bhamidipati RK, Mullangi R, Richter W, Srinivas NR.
Drug Res. (Stuttg.), DOI 10.1055/s-0043-108124.
Abstract

Disposition of levetiracetam in healthy adult horses.
Cesar FB, Stewart AJ, Boothe DM, Ravis WR, Duran SH, Wooldridge AA.
Vet. Pharmacol. Ther., DOI 10.1111/jvp.12417.
Abstract

Pharmacokinetics of buprenorphine following constant rate infusion for postoperative analgesia in dogs undergoing ovariectomy.
Barbarossa A, Rambaldi J, Giunti M, Zaghini A, Cunto M, Zambelli D, Valgimigli S, Santoro F, Romagnoli N.
Vet. Anaesth. Analg., DOI 10.1016/j.vaa.2016.05.010.
Abstract

Daily rhythms of behavioral and hormonal patterns in male dromedary camels housed in boxes.
Aubè L, Fatnassi M, Monaco D, Khorchani T, Lacalandra GM, Hammadi M, Padalino B.
PeerJ, DOI 10.7717/peerj.3074.
Abstract

Metoclopramide nasal spray in vitro evaluation and in vivo pharmacokinetic studies in dogs.
Li Y1, Fan X, Li W, Yang P, Zhang H, Tang D, Yin X, Sun J, Zheng A.
Pharm. Dev. Technol., DOI 10.1080/10837450.2017.1316734.
Abstract

Validated LC-MS-MS method for simultaneous analysis of 17 barbiturates in horse plasma for doping control.
Liu Y, Uboh CE, Li X, Guan F, You Y, Maylin GA, Zhu F, Soma LR.
J. Anal. Toxicol., DOI 10.1093/jat/bkx025.
Abstract

Screening of over 100 drugs in horse urine using automated on-line solid-phase extraction coupled to liquid chromatography-high resolution mass spectrometry for doping control.
Kwok WH, Choi TL, Tsoi YY, Leung GN, Wan TS.
J. Chromatogr. A, DOI 10.1016/j.chroma.2017.02.020.
Abstract

Identification of gonadotropin-releasing hormone metabolites in greyhound urine.
Palmer D, Rademaker K, Martin I, Hessell J, Howitt R.
Drug Test. Anal., DOI 10.1002/dta.2164.
Abstract

RNA sample preparation applied to gene expression profiling for the horse biological passport.
Bailly-Chouriberry L, Baudoin F, Cormant F, Glavieux Y, Loup B, Garcia P, Popot MA, Bonnaire Y.
Drug Test. Anal., 2017, 9, 1448–1455.
Abstract

Two complementary methods to control gonadotropin-releasing hormone vaccination (Improvac®) misuse in horseracing: Enzyme-linked immunosorbent assay test in plasma and steroidomics in urine.
Bailly-Chouriberry L, Loup B, Popot MA, Dreau ML, Garcia P, Bruyas JF, Bonnaire Y.
Drug Test. Anal., 2017, 9, 1432–1440.
Abstract

Comparison and validation of ELISA assays for plasma insulin-like growth factor-1 in the horse.
Baskerville CL, Bamford NJ, Harris PA, Bailey SR.
Open Vet. J., 2017, 7, 75–80.
Abstract

Pharmacokinetics and in vitro efficacy of salicylic acid after oral administration of acetylsalicylic acid in horses.
Buntenkötter K, Osmers M, Schenk I, Schänzer W, Machnik M, Düe M, Kietzmann M.
BMC Vet. Res., 2017, 13, 28.
Abstract

Advances in equine anti-doping.
Cawley A.
Drug Test. Anal., 2017, 9, 1282–1283.
Abstract

Intelligence-based anti-doping from an equine biological passport.
Cawley AT, Keledjian J.
Drug Test. Anal., 2017, 9, 1441–1447.
Abstract

Simultaneous determination of felodipine and metoprolol in beagle dog plasma by online SPE-LC-MS/MS and its application in a pharmacokinetic study.
Chen M, Zhou J, Mei L, Yu F, Xie X, Liu Y, Yang Y, Li Y, Mei X.
Anal. Sci., 2017, 33, 755–759.
Abstract

Doping control analysis of lithium in horse urine and plasma by inductively coupled plasma mass spectrometry.
Choi TL, Wong JK, Ho EN, Kwok WH, Leung GN, Curl P, Wan TS.
Drug Test. Anal., 2017, 9, 1407–1411.
Abstract

Pharmacokinetics of dextromethorphan and its metabolites in horses following a single oral administration.
Corado CR, McKemie DS, Knych HK.
Drug Test. Anal., 2017, 9, 880–887.
Abstract

Pharmacokinetics and pharmacodynamics of the injectable formulation of methadone hydrochloride and methadone in lipid nanocarriers administered orally to horses.
Crosignani N, Luna SP, Dalla Costa T, Pimenta EL, Detoni CB, Guterres SS, Puoli Filho JN, Pantoja JC, Pigatto MC.
J. Vet. Pharmacol. Ther., 2017, 40, 398–405.
Abstract

Pharmacokinetics and tolerability of a new formulation of omeprazole in the horse.
Di Salvo A, Busechian S, Zappulla F, Marchesi MC, Pieramati C, Orvieto S, Boveri M, Predieri PG, Rueca F, Della Rocca G.
J. Vet. Pharmacol. Ther., 2017, 40, 348–355.
Abstract

Determination of AZD6118 in dog plasma samples utilizing microextraction by packed sorbent and liquid chromatography-electrospray ionization tandem mass spectrometry.
El Beqqali A, Ahmadi M, Abdel-Rehim M.
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2017, 1043, 20–24.
Abstract

Comparison of the pharmacokinetics of two formulations of hydroxyethyl starch in healthy horses.
Epstein KL, Bergren A, Nie B, Arnold RD, Brainard DM.
J. Vet. Pharmacol. Ther., 2017, 40, 309–313.
Abstract

Detection and pharmacokinetics of salmeterol in thoroughbred horses following inhaled administration.
Fenwick SJ, Hincks PR, Scarth JP, Wieder ME, Hillyer LL, Paine SW.
J. Vet. Pharmacol. Ther., 2017, 40, 486–492.
Abstract

Challenges in detecting substances for equine anti-doping.
Fragkaki AG, Kioukia-Fougia N, Kiousi P, Kioussi M, Tsivou M.
Drug Test. Anal., 2017, 9, 1291–1303.
Abstract

Quantification of paclitaxel and polyaspartate paclitaxel conjugate in Beagle plasma: application to a pharmacokinetic study.
Gao Y, Chen J, Zhang X, Xie H, Wang Y, Guo S.
J. Chromatogr. Sci., 2017, 55, 222–231.
Abstract

Pharmacokinetic profiles of the active metamizole metabolites in healthy horses.
Giorgi M, Aupanun S, Lee HK, Poapolathep A, Rychshanova R, Vullo C, Faillace V, Laus F.
J. Vet. Pharmacol. Ther., 2017, 40, 165–171.
Abstract

Comprehensive solid-phase extraction of multitudinous bioactive peptides from equine plasma and urine for doping detection.
Guan F, Robinson MA.
Anal. Chim. Acta, 2017, 985, 79–90.
Abstract

Confirmatory analysis of etanercept in equine plasma by LC-MS for doping control.
Guan F, Robinson MA, Soma LR.
Drug Test. Anal., 2017, 9, 1421–1431.
Abstract

Cross validation of HS-GC/MS to quantify total carbon dioxide in horse plasma.
Heffron B, Bash J, Larsen AK.
J. Anal. Toxicol., 2017, 41, 230–235.
Abstract

Dopingrelevante Substanzen in Futtermitteln für Pferde [Doping relevant substances in horse feed].
Herholz C, Zink N, Laska H, Gumpendobler M, Trolliet C, Probst S.
Schweiz. Arch. Tierheilkd., 2017, 159, 231–235.
Abstract

Pharmacokinetics and oral bioavailability of metformin hydrochloride in healthy mixed-breed dogs.
Johnston CA, Dickinson VSM, Alcorn J, Gaunt MC.
Am. J. Vet. Res., 2017, 78, 1193–1199.
Abstract

Liquid chromatography–high resolution mass spectrometry-based metabolomic approach for the detection of Continuous Erythropoiesis Receptor Activator effects in horse doping control.
Joré C, Loup B, Garcia P, Paris AC, Popot MA, Audran M, Bonnaire Y, Varlet-Marie E, Bailly-Chouriberry L.
J. Chromatogr. A, 2017, 1521, 90–99.
Abstract

Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study.
Kenward H, Elliott J, Lee T, Pelligand L.
EMC Vet. Res., 2017, 13, 244.
Abstract

Pharmacokinetics and selected pharmacodynamics of trazodone following intravenous and oral administration to horses undergoing fitness training.
Knych HK, Mama KR, Steffey EP, Stanley SD, Kass PH.
Am. J. Vet. Res., 2017, 78, 1182–1192.
Abstract

Disposition of the anti-ulcer medications ranitidine, cimetidine, and omeprazole following administration of multiple doses to exercised Thoroughbred horses.
Knych HK, Stanley SD, Arthur RM, McKemie DS.
J. Vet. Pharmacol. Ther., 2017, 40, 92–96.
Abstract

Pharmacokinetics of betamethasone in plasma, urine, and synovial fluid following intra-articular administration to exercised thoroughbred horses.
Knych HK, Stanley SD, Harrison LM, McKemie DS.
Drug Test. Anal., 2017, 9, 1385–1391.
Abstract

Pharmacokinetics and pharmacodynamics of meldonium in exercised thoroughbred horses.
Knych HK, Stanley SD, McKemie DS, Arthur RM, Bondesson U, Hedeland M, Thevis M, Kass PH.
Drug Test. Anal., 2017, 9, 1392–1399.
Abstract

Pharmacokinetic and pharmacodynamics of xylazine administered to exercised thoroughbred horses.
Knych HK, Stanley SD, McKemie DS, Arthur RM, Kass PH.
Drug Test. Anal., 2017, 9, 713–720.
Abstract

Pharmacokinetics and selected pharmacodynamics of romifidine following low-dose intravenous administration in combination with exercise to quarter horses.
Knych HK, Stanley SD, McKemie DS, Steinmetz SJ.
J. Vet. Pharmacol. Ther., 2017, 40, 569–574.
Abstract

Racing chemistry: A century of challenges and progress.
Kremmer C.
Drug Test. Anal., 2017, 9, 1284–1290.
Abstract

In vitro phase I metabolism of selective estrogen receptor modulators in horse using ultra-high performance liquid chromatography-high resolution mass spectrometry.
Kwok KY, Chan GH, Kwok WH, Wong JK, Wan TS.
Drug Test. Anal., 2017, 9, 1349–1362.
Abstract

Detection of anabolic and androgenic steroids and/or their esters in horse hair using ultra-high performance liquid chromatography-high resolution mass spectrometry.
Kwok KY, Choi TL, Kwok WH, Wong JK, Wan TS.
J. Chromatogr. A, 2017, 14, 76–86.
Abstract

Simultaneous detection of xenon and krypton in equine plasma by gas chromatography-tandem mass spectrometry for doping control.
Kwok WH, Choi TLS, So PK, Yao ZP, Wan TSM.
Drug Test. Anal., 2017, 9, 317–322.
Abstract

Control of methylxanthines in the competition horse: pharmacokinetic/pharmacodynamic studies on caffeine, theobromine and theophylline for the assessment of irrelevant concentrations.
Machnik M, Kaiser S, Koppe S, Kietzmann M, Schenk I, Düe M, Thevis M, Schänzer W, Toutain PL.
Drug Test. Anal., 2017, 9, 1372–1384.
Abstract

Pharmacokinetic and pharmacodynamic properties of pergolide mesylate following long-term administration to horses with pituitary pars intermedia dysfunction.
McFarlane D, Banse H, Knych HK, Maxwell LK.
J. Vet. Pharmacol. Ther., 2017, 40, 158–164.
Abstract

Interlaboratory trial for the measurement of total cobalt in equine urine and plasma by ICP-MS.
Popot MA, Ho ENM, Stojiljkovic N, Bagilet F, Remy P, Maciejewski P, Loup B, Chan GHM, Hargrave S, Arthur RM, Russo C, White J, Hincks P, Pearce C, Ganio G, Zahra P, Batty D, Jarrett M, Brooks L, Prescott LA, Bailly-Chouriberry L, Bonnaire Y, Wan TSM.
Drug Test. Anal., 2017, 9, 1400–1406.
Abstract

Pharmacokinetics of ketamine and norketamine enantiomers after racemic or S-ketamine IV bolus administration in dogs during sevoflurane anaesthesia.
Romagnoli N, Bektas RN, Kutter AP, Barbarossa A, Roncada P, Hartnack S, Bettschart-Wolfensberger R.
Res. Vet. Sci., 2017, 112, 208–213.
Abstract

Transcriptome profiling of Arabian horse blood during training regimens.
Ropka-Molik K, Stefaniuk-Szmukier M, ┼╗ukowski K, Piórkowska K, Gurgul A, Bugno-Poniewierska M.
BMC Genet., 2017, 18, 31.
Abstract

Quantification of dimethylsulfoxide (DMSO) in equine plasma and urine using HILIC-MS/MS.
Salomonsson ML, Bondesson U, Hedeland M.
Drug Test. Anal., 2017, 9, 935–941.
Abstract
Correction in Drug Test. Anal., 2017, 9, 1472.
Abstract

Determination of rabeprazole enantiomers in dog plasma by supercritical fluid chromatography tandem mass spectrometry and its application to a pharmacokinetic study.
Su C, Yang H, Meng X, Fawcett JP, Cao J, Yang Y, Gu J.
J. Sep. Sci., 2017, 40, 1010–1016.
Abstract

The effects of dose and diet on the pharmacokinetics of omeprazole in the horse.
Sykes BW, Underwood C, McGowan CM, Mills PC.
J. Vet. Pharmacol. Ther., 2017, 40, 172–178.
Abstract

Application of testosterone to epitestosterone ratio to horse urine - a complementary approach to detect the administrations of testosterone and its pro-drugs in Thoroughbred geldings.
Viljanto M, Scarth J, Hincks P, Hillyer L, Cawley A, Suann C, Noble G, Walker CJ, Kicman AT, Parkin MC.
Drug Test. Anal., 2017, 9, 1328–1336.
Abstract

A review of designer anabolic steroids in equine sports.
Waller CC, McLeod MD.
Drug Test. Anal., 2017, 9, 1304–1319.
Abstract

Determination of vitacoxib, a novel COX-2 inhibitor, in equine plasma using UPLC-MS/MS detection: Development and validation of new methodology.
Wang J, Zhao T, Kong J, Peng H, Lv P, Li J, Cao X, Zhang S.
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2017, 1061–1062, 270–274.
Abstract

Equine performance genes and the future of doping in horseracing.
Wilkin T, Baoutina A, Hamilton N.
Drug Test. Anal., 2017, 9, 1456–1471.
Abstract

Identification of porcine relaxin in plasma by liquid chromatography-high resolution mass spectrometry.
Wong AS, Ho EN, Kwok WH, Leung GN, Shen Y, Qi RZ, Yue SK, Wan TS.
Drug Test. Anal., 2017, 9, 1412–1420.
Abstract

Doping control analysis of anabolic steroids in equine urine by gas chromatography-tandem mass spectrometry.
Wong AS, Leung GN, Leung DK, Wan TS.
Drug Test. Anal., 2017, 9, 1320–1327.
Abstract

Doping control study of AICAR in postrace urine and plasma samples from horses.
Wong JK, Kwok WH, Chan GH, Choi TL, Ho EN, Jaubert M, Bailly-Chouriberry L, Bonnaire Y, Cawley A, Williams HM, Keledjian J, Brooks L, Chambers A, Lin Y, Wan TS.
Drug Test. Anal., 2017, 9, 1363–1371.
Abstract

Evidence of boldenone, nandrolone, 5(10)-estrene-3β-17α-diol and 4-estrene-3,17-dione as minor metabolites of testosterone in equine.
Wong JKY, Leung DKK, Curl P, Schiff PJ, Lam KKH, Wan TSM.
Drug Test. Anal., 2017, 9, 1337–1348.
Abstract

Quantitation of γ-aminobutyric acid in equine plasma by hydrophilic interaction liquid chromatography with tandem mass spectrometry.
Yi R, Zhao S, Kong N, Zhang J, Loganathan D, Mérette S, Morrissey B.
J. Sep. Sci., 2017, 40, 3183–3368.
Abstract

Serial-omics characterization of equine urine.
Yuan M, Breitkopf SB, Asara JM.
PLoS One, 2017, 12, e0186258.
Abstract

Capromorelin increases food consumption, body weight, growth hormone, and sustained insulin-like growth factor 1 concentrations when administered to healthy adult Beagle dogs.
Zollers B, Rhodes L, Smith RG.
J. Vet. Pharmacol. Ther., 2017, 40, 140–147.
Abstract