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2026 Articles

Accepted articles

LC-HRMS detection of three ionizable lipids in equine plasma: surrogate markers for long-term LNP-mediated gene-doping surveillance.
Shimizu Y, Furukawa R, Kikuchi M, Sugai-Bannai M, Hirano-Kodaira M, Tozaki T, Leung GN.
Anal. Bioanal. Chem., DOI 10.1007/s00216-026-06556-5.
Abstract

Direct LC-HRMS/MS characterisation and RT-qPCR detection for potential mRNA-based doping agent.
Yuen BP, Wong KS, Lin VY, Cheung HW, Ho EN, Wong WT.
Anal. Bioanal. Chem., DOI 10.1007/s00216-026-06513-2.
Abstract

Influence of tramadol on the intravenous pharmacokinetics of dipyrone active metabolites in dogs.
Mouta AN, Arcoverde KN, Dos Anjos Honorato R, Fernandes NS, de Oliveira CVA, Mesquita GC, Passos YDB, Araújo-Silva G, de Paula VV.
J. Vet. Pharmacol. Ther., DOI 10.1111/jvp.70073.
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Erythrocyte sequestration of metformin in horses: impact on matrix-specific pharmacokinetics and detection windows.
Jacobs ME, Blea J, Hardy M, McKemie DS, Traynham M, Knych HK.
BMC Vet. Res., DOI 10.1186/s12917-026-05449-0.
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Pharmacokinetics of intramuscularly administered ketamine at subanaesthetic dosage in horses.
Vandaele Z, Flyps J, Cuypers C, De Baere S, Devreese M, Schauvliege S.
J. Vet. Pharmacol. Ther., DOI 10.1111/jvp.70070.
Abstract

Effects of oral single-dose empagliflozin on urinary glucose, serum β-hydroxybutyrate, and plasma empagliflozin concentrations in healthy adult dogs.
Plá Gutierrez AD, M. O'Sullivan L, Côté E, McConkey S, KuKanich B, Martinez SE.
J. Vet. Pharmacol. Ther., DOI 10.1111/jvp.70066.
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Plasma and urinary elimination profiles of medetomidine metabolites in horses for the purpose of doping and medication control.
Minamijima Y, Kuroda T, Maeda Y, Narita S, Yamashita S, Yamada M.
J. Vet. Pharmacol. Ther., DOI 10.1111/jvp.70063.
Abstract

The pharmacokinetics of intravenous and subcutaneous ondansetron in female beagle dogs.
Landau ED, Boege KR, Messenger K, Ballash G, Gustafson D, Pereira CR, Banks K, Aarnes T, Lerche P, Midon M, Muñoz KA.
J. Vet. Pharmacol. Ther., DOI 10.1111/jvp.70058.
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Vonoprazan pharmacokinetics and effects on gastric pH following administration to fed and fasted horses.
Morales CJ, Sykes BW, McKemie DS, Kass PH, Knych HK.
Equine Vet. J., DOI 10.1111/evj.70128.
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Published articles

Pharmacokinetics of ilunocitinib, a new Janus kinase inhibitor, in dogs.
Boerngen K, Patel Y, Pittorino M, Toutain CE.
J. Vet. Pharmacol. Ther., 2026, 49, 7-16.
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Determination and pharmacokinetic of peiminine in beagle dogs by UPLC-MS/MS.
Cheng Q, Peng X, Li X, Jia X.
Int. J. Anal. Chem., 2026, 2026, 4144078.
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Metabolite profiling and identification of semaglutide in liver S9 across species and rat plasma.
Cong Y, Tang C, Li Z, Gao Y, Chen L, Xu H, Diao X.
Biomed Chromatogr., 2026, 40, e70415.
Abstract

Comparative pharmacokinetics of intranasal or intramuscular atipamezole in unsedated dogs and efficacy for reversal of xylazine sedation.
Cowan VE, Mitcham VR, Michel DL, Lyons C, Kennedy J, Reyes Morales YC, Loewen JM, Chicoine AL.
J. Vet. Pharmacol. Ther., 2026, 49, 257-266.
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Differences in plasma exposure of cannabidiol and cannabidiolic acid following oral administration to horses.
Ekstrand C, Michanek P, Hernlund E, Gehring R, Spjut K, Salomonsson M.
J. Vet. Pharmacol. Ther., 2026, 49, 22-32.
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Bioavailability of oral ondansetron in dogs: A crossover study.
Garrick A, Zersen K, Gustafson D, Quimby J, Diaz A, Shropshire S.
J. Vet. Pharmacol. Ther., 2026, 49, 17-21.
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Exposure to subcutaneously administered butorphanol in horses pre-treated with detomidine or detomidine-vatinoxan.
Honkavaara JM, Karikoski NP, Palvas L, Pypendop BH, Rinne VM, Raekallio MR.
J. Vet. Pharmacol. Ther., 2026, 49, 289-294.
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A first report of the misuse of a novel synthetic glucocorticoid, 9α-fluoro-6α-methylprednisolone, in camel racing.
Ishii H, Basgallop NJ, Kelly RP, Todoroki K, Alshamsi NS, McKinney AR.
Drug Test. Anal., 2026, 18, 270-286.
Abstract

Metformin in the horse: Pharmacokinetics and detection times using Monte Carlo simulations.
Jacobs ME, Blea J, Hardy M, McKemie DS, Traynham M, Knych HK.
Drug Test. Anal., 2026, 18, 139-148.
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Analytical challenges and emerging detection strategies of synthetic cannabinoids in horse doping control.
Kabil E, Ural MN, Göktaş EF.
Biomed. Chomatogr., 2026, 40, e70432.
Abstract

Pharmacokinetics of remimazolam versus midazolam after intravenous administration to horses.
Kawashima M, Kuroda T, Minamijima Y, Yamazaki Y, Mita H, Nomura M, Ohta M.
J. Vet. Pharmacol. Ther., 2026, 49, 94-98.
Abstract

A meta-analysis of international flunixin pharmacokinetics in horses: Toward regulatory harmonization and individualized detection times using Bayesian paradigm.
Kuroda T, Knych HK, Noble GK, Minamijima Y, Leung GNW, Nomura M, Mizobe F, Ishikawa Y, Kusano K, Toutain PL.
Drug Test. Anal., 2026, 18, 32-50.
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Pharmacokinetics of topical administration of altrenogest in mares and implications for human health.
Loy J, Sornalingam K, Cawley A, Scrivener C, Keledjian J, Noble GK.
J. Vet. Pharmacol. Ther., 2026, 49, 274-281.
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Plasma and urine pharmacokinetics of intravenous pridinol in Thoroughbreds for its medication control.
Minamijima Y, Kuroda T, Okano A, Wakuno A, Yuasa R, Ishikawa Y, Nomura M, Kinoshita K, Yamada M.
J. Vet. Pharmacol. Ther., 2026, 49, 1-6.
Abstract

Plasma concentrations following oral administration of two different forms of resveratrol in horses.
Mochal-King C, Strunk R, Paul L.
J. Equine Vet. Sci., 2026, 161, 105859.
Abstract

Sensitive and selective quantification of elcatonin in equine plasma and urine using LC-FAIMS-MS/MS.
Ohnuma K, Fukazawa M, Uchida T, Kato T, Sugai-Bannai M, Shibuya M, Yamada M, Hirano-Kodaira M.
J. Pharm. Biomed. Anal., 2026, 279, 117551.
Abstract

Plasma pharmacokinetics of topical 0.1% diclofenac sodium and 0.5% ketorolac tromethamine in dogs.
Peraza J, Ross MK, Langston VC, Wills R, Fischer D, Cassen C, Betbeze C.
Vet. Opthalmol., 2026, 29, e70105.
Abstract

Pharmacokinetics and safety of a single subcutaneous or intramuscular dose of ketamine in healthy horses.
Rangel A, Sellon DC, Sanz MG, Pinnell E, Pietras ZM, Villarino NF.
J. Vet. Pharmacol. Ther., 2026, 49, 141-149.
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Gene editing and the future of Thoroughbred breeding and racing.
Ryder E, Given J, Hamilton N.
Drug Test. Anal., 2026, 18, 646-651.
Abstract

Efficacy, pharmacokinetics and safety of liposomal synthetic cannabidiol injected subcutaneously in dogs: a randomized, blinded, placebo-controlled, crossover clinical trial.
Shilo-Benjamini Y, Milgram J, Lavy E, Quint M, Barasch D, Cern A, Barenholz Y.
Front. Vet. Sci., 2026, 12, 1746266.
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Supramolecular solvent extraction for doping control analysis of prohibited substances in horse urine.
So YM, Kwok WH, Yuen SMS, Wong COL, Ho ENM.
Drug Test. Anal., 2026, 18, 652-668.
Abstract

Detection of nandrolone decanoate and its metabolites in equine hair after intramuscular administration.
So YM, Kwok WH, Yuen SMS, Wong COL, Wan TSM, Ho ENM.
Drug Test. Anal., 2026, 18, 149-158.
Abstract

Pharmacokinetics and anti-inflammatory effects of intramuscular betamethasone in exercised Thoroughbred horses.
Sullivan J, Blea J, McKemie DS, Kass PH, Knych HK.
J. Vet. Pharmacol. Ther., 2026, 49, 295-305.
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Special issue "gene doping control".
Tozaki T.
Int. J. Mol. Sci., 2026, 27, 2631.
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Pharmacokinetics of ropivacaine after intraperitoneal instillation in anaesthetized dogs: a randomized clinical trial.
Verdier N, Hummel K, Al-Jalali V, Claaßen S, Donati PA, Portela DA, Razzazi-Fazeli E, Mosing M.
Vet. Anaesth. Analg., 2026, 53, 101146.
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Single-dose pharmacokinetics of intranasal levetiracetam in healthy dogs.
Wagner JL, Foss KD, Reinhart JM, Forsythe LE.
J. Vet. Pharmacol. Ther., 2026, 49, 110-119.
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Population pharmacokinetics of sildenafil in dogs with naturally occurring pulmonary hypertension.
Yata M, DeFrancesco TC, Bonagura JD, Papich MG.
J. Vet. Pharmacol. Ther., 2026, 49, 267-273.
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